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1. (WO2003091189) CANNABINOIDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2003/091189    International Application No.:    PCT/US2002/019569
Publication Date: 06.11.2003 International Filing Date: 20.06.2002
Chapter 2 Demand Filed:    19.11.2003    
IPC:
C07D 303/10 (2006.01), C07D 309/06 (2006.01), C07D 309/22 (2006.01), C07D 317/72 (2006.01), C07D 333/16 (2006.01), C07D 335/02 (2006.01)
Applicants: VIRGINIA COMMONWEALTH UNIVERSITY [US/US]; 1101 EAST Marshall Street Room 1-026 Richmond, VA 23298-0568 (US) (For All Designated States Except US).
MARTIN, Billy, R. [US/US]; (US) (For US Only).
RAZDAN, Raj, K. [US/US]; (US) (For US Only)
Inventors: MARTIN, Billy, R.; (US).
RAZDAN, Raj, K.; (US)
Agent: MITCHARD, Leonard, C.; Nixon & Vanderhye, 1100 North Glebe Road, Suite 800, Arlington, VA 22201-4714 (US)
Priority Data:
60/375,012 25.04.2002 US
Title (EN) CANNABINOIDS
(FR) CANNABINOIDES
Abstract: front page image
(EN)Compounds of the formula: wherein R, R1 and R4 are defined in the specification, and pharmaceutically acceptable salts, esters and tautomers thereof, having activity at peripheral cannabinoid receptors, commonly designated the CB2 receptor class. The compounds are useful for therapy, especially in the treatment of pain, inflammation and autoimmune disease.
(FR)L'invention concerne des composés de formule (I), dans laquelle R, R1 et R4 sont tels que définis dans la description, ainsi que des sels, des esters et des tautomères de ces composés, ces substances étant pharmaceutiquement acceptables et développant une activité sur les récepteurs cannabinoïdes périphériques communément désignés par la classe de récepteurs CB2. Ces composés s'avèrent utiles en thérapie, notamment pour le traitement des douleurs, des inflammations et de maladies auto-immunes.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)