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1. (WO2001045725) TREATMENT FOR INFLAMMATORY BOWEL DISEASE (IBD) AND RELATED CONDITIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/045725    International Application No.:    PCT/US2000/034792
Publication Date: 28.06.2001 International Filing Date: 20.12.2000
Chapter 2 Demand Filed:    19.07.2001    
IPC:
A61P 1/00 (2006.01), A61P 19/00 (2006.01), A61P 29/00 (2006.01), A61P 31/12 (2006.01), A61P 9/00 (2006.01)
Applicants: ANCILE PHARMACEUTICALS, INC. [US/US]; Suite B, 10555 Science Center Drive, San Diego, CA 92121 (US) (For All Designated States Except US).
BASU, Amaresh [US/US]; (US) (For US Only).
HOFFMAN, Keith [US/US]; (US) (For US Only)
Inventors: BASU, Amaresh; (US).
HOFFMAN, Keith; (US)
Agent: REISMAN, Joseph, M.; Knobbe, Martens, Olson & Bear, LLP, 16th Floor, 620 Newport Center Drive, Newport Beach, CA 92660 (US)
Priority Data:
60/173,006 23.12.1999 US
Title (EN) TREATMENT FOR INFLAMMATORY BOWEL DISEASE (IBD) AND RELATED CONDITIONS
(FR) TRAITEMENT DES MALADIES INTESTINALES INFLAMMATOIRES (IBD) ET DES ETATS APPARENTES
Abstract: front page image
(EN)Compositions, including formulations, of plants for the treatment of Inflammatory Bowel Disease, Irritable Bowel Syndrome, and inflammatory and other related conditions, such as arthritis, are disclosed. The formulations consist of one or both of the two herbs Chen Pi Citrus reticulata and Wu Mei Prunus mume, which, according to the invention, possess significant cytokine TNF-$g(a) inhibitory activity. The formulations also may include one or more of the following herbs which, according to the invention, inhibit PGE¿2?: Hou Po Magnoliae officinalis, Huang Bai Phellodendron chinense, Huang Lian Coptis chinensis, Huo Xiang Agastaches rugosa, Pao Jiang Zingiberis officinalis, Qin Pi Fraxinus rynchophylla, and Zhi Gan Cao Glycyrhizae inflata.
(FR)Cette invention se rapporte à des compositions, y compris des formulations, de plantes pour le traitement des maladies intestinales inflammatoires, du syndrome du côlon irritable et des états inflammatoires et autres états apparentés, tels que l'arthrite. Ces formulations contiennent l'une et/ou l'autre des deux herbes Chen Pi ($m(f)i$m(g)Citrus reticulata$m(f)/i$m(g)) et Wu Mei ($m(f)i$m(g)Prunus mume$m(f)/i$m(g)), qui, selon cette invention, possèdent une action inhibitrice importante du facteur TNF-$g(a) à base de cytokines. Ces formulations peuvent également contenir une ou plusieurs des herbes suivantes qui, selon cette invention, inhibent la prostaglandine E¿2? (PGE)¿2?: Hou Po ($m(f)i$m(g)Magnoliae officinalis$m(f)/i$m(g)), Huang Bai ($m(f)i$m(g)Phellodendron chinense$m(f)/i$m(g)), Huang Lian ($m(f)i$m(g)Coptis chinensis$m(f)/i$m(g)), Huo Xiang ($m(f)i$m(g)Agastaches rugosa$m(f)/i$m(g)), Pao Jiang ($m(f)i$m(g)Zingiberis officinalis$m(f)/i$m(g)), Qin Pin ($m(f)i$m(g)Fraxinus rynchophylla$m(f)/i$m(g)), et Zhi Gan Cao ($m(f)i$m(g)Glycyrhizae inflata$m(f)/i$m(g)).
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Org. (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)